NSUN5 Polyclonal Antibody

Rabbit Anti-NSUN5 Polyclonal Antibody

Product Specifications

Background

NSUN5 (NOP2/Sun RNA Methyltransferase Family Member 5) encodes a member of an evolutionarily conserved family of proteins that may function as methyltransferases. NSUN5 is located in a larger region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. There are two pseudogenes for NSUN5 located in the same region of chromosome 7. Alternative splicing results in multiple transcript variants encoding different isoforms.

CAS Number

9007-83-4

Product Name Alternative

Probable 28S rRNA (cytosine-C (5) ) -methyltransferase; NOL1-related protein; NOL1R; NOL1/NOP2/Sun domain family member 5; Williams-Beuren syndrome chromosomal region 20A protein

Gene ID

55695

Accession Number

Q96P11

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NSUN5 protein at amino acid sequence of 320-400

Clonality

Polyclonal

Tag

NSUN5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

47kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NSUN5 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Probable 28S rRNA (cytosine-C (5) ) -methyltransferase; NOL1-related protein; NOL1R; NOL1/NOP2/Sun domain family member 5; Williams-Beuren syndrome chromosomal region 20A protein