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NRX1B Polyclonal Antibody

Rabbit Anti-NRX1B Polyclonal Antibody

Product Specifications

Background

NRXN1 (Neurexin 1) is a Protein Coding gene. Diseases associated with NRXN1 include Pitt-Hopkins-Like Syndrome 2 and Schizophrenia 17. Among its related pathways are Muscular Dystrophies and Dystrophin-Glycoprotein Complex and Cell adhesion molecules (CAMs) . NRXN1 encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca (2+) -dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts.

CAS Number

9007-83-4

Product Name Alternative

Neurexin-1-beta; Neurexin I-beta

Gene ID

9378

Accession Number

P58400

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human NRX1B protein at amino acid sequence of 260-340

Clonality

Polyclonal

Tag

NRX1B

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

48kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NRX1B protein

Observed Molecular Weight

48

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Neurexin-1-beta; Neurexin I-beta

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P58400

Isotype

Rabbit IgG

Available Sizes

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