NR2E3 Polyclonal Antibody

Rabbit Anti-NR2E3 Polyclonal Antibody

Product Specifications

Background

Nuclear Receptor Subfamily 2 Group E Member 3 is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. NR2E3 encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in NR2E3 are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

CAS Number

9007-83-4

Product Name Alternative

Photoreceptor-specific nuclear receptor; Nuclear receptor subfamily 2 group E member 3; Retina-specific nuclear receptor

Gene ID

10002

Accession Number

Q9Y5X4

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human NR2E3 protein

Clonality

Polyclonal

Tag

NR2E3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of NR2E3 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000