TAM557 (TFA)
TAM557 TFA is a cytotoxic tubulysin compounds, which is modified to be used for conjugation to transport vehicles that are targeting molecules, such as proteins, peptides, small molecules or polymeric carriers which can carry a targeting principle[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tam557-tfa.html
Purity
99.53
Solubility
10 mM in DMSO
Smiles
O=C([C@@H]1N(CCCC1)C)N[C@@H]([C@@H](C)CC)C(N(CCC)[C@@H](C(C)C)C[C@H](C2=NC(C(N[C@H](C[C@H](C)C(NNC(OCCOCCOCCOCCN)=O)=O)CC3=CC=C(C=C3)O)=O)=CS2)OCCC)=O.O=C(O)C(F)(F)F
Molecular Formula
C52H85F3N8O13S
Molecular Weight
1119.34
References & Citations
[1]Wolfgang Richter, et al., Cytotoxic tubulysin compounds and conjugates thereof. Patent WO2015113760A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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