MYL2 Polyclonal Antibody

Rabbit Anti-MYL2 Polyclonal Antibody

Product Specifications

Background

MYL2 (Myosin Light Chain 2) is a Protein Coding gene. Diseases associated with MYL2 include Cardiomyopathy, Hypertrophic, 10 and Congenital Fiber-Type Disproportion. Among its related pathways are Focal Adhesion and Sertoli-Sertoli Cell Junction Dynamics. Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in MYL2 are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy.

CAS Number

9007-83-4

Product Name Alternative

Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; MLC-2; MLC-2v

Gene ID

4633

Accession Number

P10916

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human MYL2 protein at amino acid sequence of 91-140

Clonality

Polyclonal

Tag

MYL2

Applications

WB, ELISA, IHC

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

18kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MYL2

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000