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MYCN Polyclonal Antibody

Rabbit Anti-MYCN Polyclonal Antibody

Product Specifications

Background

MYCN gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Product Name Alternative

N-myc proto-oncogene protein; Class E basic helix-loop-helix protein 37; bHLHe37

Gene ID

4613

Accession Number

P04198

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human MYCN protein

Clonality

Polyclonal

Tag

MYCN

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

51kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MYCN protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP59357.pdf

Observed Molecular Weight

51

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

N-myc proto-oncogene protein; Class E basic helix-loop-helix protein 37; bHLHe37

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P04198

CAS Number

9007-83-4

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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