MEPE Polyclonal Antibody

Rabbit Anti-MEPE Polyclonal Antibody

Product Specifications

Background

MEPE encodes a secreted calcium-binding phosphoprotein that belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family of proteins. Members of this family are components of the extracellular matrix of bone and dentin and regulate bone mineralization. Deficiency of a similar protein in mouse results in increased bone mass. Mice lacking MEPE are resistant to aging-related trabecular bone loss. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Matrix extracellular phosphoglycoprotein; Osteoblast/osteocyte factor 45; OF45

Gene ID

56955

Accession Number

Q9NQ76

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human MEPE protein at amino acid sequence of 20-100

Clonality

Polyclonal

Tag

MEPE

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MEPE protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000