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MARCO Polyclonal Antibody

Rabbit Anti-MARCO Polyclonal Antibody

Product Specifications

Background

The protein encoded by MARCO (Macrophage Receptor With Collagenous Structure) is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

CAS Number

9007-83-4

Product Name Alternative

Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2

Gene ID

8685

Accession Number

Q9UEW3

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human MARCO protein at amino acid sequence of 380-460

Clonality

Polyclonal

Tag

MARCO

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of MARCO protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP59218.pdf

Observed Molecular Weight

57

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Macrophage receptor MARCO; Macrophage receptor with collagenous structure; Scavenger receptor class A member 2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q9UEW3

Isotype

Rabbit IgG

Available Sizes

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