LSM1 Polyclonal Antibody

Rabbit Anti-LSM1 Polyclonal Antibody

Product Specifications

Background

LSM1 encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo (U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of LSM1 may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for LSM1, and a pseudogene of LSM1 is located on the short arm of chromosome 9.

CAS Number

9007-83-4

Product Name Alternative

U6 snRNA-associated Sm-like protein LSm1; Cancer-associated Sm-like; Small nuclear ribonuclear CaSm

Gene ID

27257

Accession Number

O15116

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human LSM1 protein at amino acid sequence of 50-130

Clonality

Polyclonal

Tag

LSM1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

14kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of LSM1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000