LRRK2 Polyclonal Antibody
Rabbit Anti-LRRK2 Polyclonal Antibody
Product Specifications
Background
LRRK2 is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. Leucine Rich Repeat Kinase 2 is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
CAS Number
9007-83-4
Product Name Alternative
Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin
Gene ID
120892
Accession Number
Q5S007
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human LRRK2 protein
Clonality
Polyclonal
Tag
LRRK2
Applications
IHC, IF
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
277kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of LRRK2 protein
Observed Molecular Weight
277
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300; IF 1:50-200
Other Product Names
Leucine-rich repeat serine/threonine-protein kinase 2; Dardarin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5S007
Isotype
Rabbit IgG
Available Sizes
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