(R) -ONO-2952
(R) -ONO-2952 is a R-enantiomer of ONO-2952. ONO-2952 is a potent, selective and orally active TSPO antagonist with Kis of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes[1].
Product Specifications
CAS Number
2988224-39-9
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-ono-2952.html
Purity
99.81
Solubility
DMSO : 220 mg/mL (ultrasonic)
Smiles
CC(N1CC2(CC2)C3=C(NC4=CC=CC(F)=C43)[C@H]1C5=C(C=C(C=C5)Cl)OC)=O
Molecular Formula
C22H20ClFN2O2
Molecular Weight
398.86
References & Citations
[1]Mitsui K, et al. Anti-stress effects of ONO-2952, a novel translocator protein 18 kDa antagonist, in rats. Neuropharmacology. 2015 Dec;99:51-66.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
RING finger protein unkempt like (UNKL) Rabbit Polyclonal Antibody
