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INSL3 Polyclonal Antibody

Rabbit Anti-INSL3 Polyclonal Antibody

Product Specifications

Background

INSL3 encodes a member of the insulin-like hormone superfamily. The encoded protein is mainly produced in gonadal tissues. Studies of the mouse counterpart suggest that INSL3 may be involved in the development of urogenital tract and female fertility. This protein may also act as a hormone to regulate growth and differentiation of gubernaculum, and thus mediating intra-abdominal testicular descent. Mutations in INSL3 may lead to cryptorchidism. Alternate splicing results in multiple transcript variants. INSL3 (Insulin Like 3) is a Protein Coding gene. Diseases associated with INSL3 include Cryptorchidism and Testicular Cancer. Among its related pathways are G alpha (s) signalling events and Signaling by GPCR.

CAS Number

9007-83-4

Product Name Alternative

Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor

Gene ID

3640

Accession Number

P51460

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human INSL3 protein at amino acid sequence of 10-50

Clonality

Polyclonal

Tag

INSL3

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of INSL3

Product Datasheet

https://www.abbkine.com/datasheet/ABP58945.pdf

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200

Other Product Names

Insulin-like 3; Leydig insulin-like peptide; Ley-I-L; Relaxin-like factor

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P51460

Isotype

Rabbit IgG

Available Sizes

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