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I27RA Polyclonal Antibody

Rabbit Anti-I27RA Polyclonal Antibody

Product Specifications

Background

In mice, CD4+ helper T-cells differentiate into type 1 (Th1) cells, which are critical for cell-mediated immunity, predominantly under the influence of IL12. Also, IL4 influences their differentiation into type 2 (Th2) cells, which are critical for most antibody responses. Mice deficient in these cytokines, their receptors, or associated transcription factors have impaired, but are not absent of, Th1 or Th2 immune responses. IL27RA encodes Interleukin 27 Receptor Subunit Alpha which is similar to the mouse T-cell cytokine receptor Tccr at the amino acid level, and is predicted to be a glycosylated transmembrane protein.

CAS Number

9007-83-4

Product Name Alternative

Interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; Cytokine receptor WSX-1; Cytokine receptor-like 1; Type I T-cell cytokine receptor; TCCR; ZcytoR1

Gene ID

9466

Accession Number

Q6UWB1

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human I27RA protein

Clonality

Polyclonal

Tag

I27RA

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

69kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of I27RA protein

Observed Molecular Weight

69

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; Cytokine receptor WSX-1; Cytokine receptor-like 1; Type I T-cell cytokine receptor; TCCR; ZcytoR1

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q6UWB1

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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