HEXI2 Polyclonal Antibody

Rabbit Anti-HEXI2 Polyclonal Antibody

Product Specifications

Background

HEXIM2 encodes a member of the HEXIM family of proteins. Hexamethylene Bisacetamide Inducible 2 is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Protein HEXIM2; Hexamethylene bis-acetamide-inducible protein 2

Gene ID

124790

Accession Number

Q96MH2

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human HEXI2 protein at amino acid sequence of 100-180

Clonality

Polyclonal

Tag

HEXI2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

31kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of HEXI2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000