HECAM Polyclonal Antibody

Rabbit Anti-HECAM Polyclonal Antibody

Product Specifications

Background

The protein encoded by HEPACAM is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of HEPACAM is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.

CAS Number

9007-83-4

Product Name Alternative

Hepatocyte cell adhesion molecule; Protein hepaCAM

Gene ID

220296

Accession Number

Q14CZ8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human HECAM protein at amino acid sequence of 10-90

Clonality

Polyclonal

Tag

HECAM

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

45kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of HECAM protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000