GTSE1 Polyclonal Antibody

Rabbit Anti-GTSE1 Polyclonal Antibody

Product Specifications

Background

The protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. GTSE1 (G2 And S-Phase Expressed 1) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and CDK-mediated phosphorylation and removal of Cdc6.

CAS Number

9007-83-4

Product Name Alternative

G2 and S phase-expressed protein 1; GTSE-1; Protein B99 homolog

Gene ID

51512

Accession Number

Q9NYZ3

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human GTSE1 protein at amino acid sequence of 70-150

Clonality

Polyclonal

Tag

GTSE1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

79kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GTSE1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000