GRIK5 Polyclonal Antibody

Rabbit Anti-GRIK5 Polyclonal Antibody

Product Specifications

Background

GRIK5 encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. Alternative splicing results in multiple transcript variants. GRIK5 (Glutamate Ionotropic Receptor Kainate Type Subunit 5) is a Protein Coding gene. Diseases associated with GRIK5 include Schizophrenia. Among its related pathways are Circadian entrainment and Presynaptic function of Kainate receptors.

CAS Number

9007-83-4

Product Name Alternative

Glutamate receptor ionotropic, kainate 5; GluK5; Excitatory amino acid receptor 2; EAA2; Glutamate receptor KA-2; KA2

Gene ID

2901

Accession Number

Q16478

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human GRIK5 protein at amino acid sequence of 910-990

Clonality

Polyclonal

Tag

GRIK5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

107kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GRIK5 protein

Observed Molecular Weight

107

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000