GP161 Polyclonal Antibody

Rabbit Anti-GP161 Polyclonal Antibody

Product Specifications

Background

The protein encoded by GPR161 is an orphan G protein-coupled receptor whose ligand is unknown. GPR161 is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, GPR161 is a potential drug target for triple-negative breast cancer.

CAS Number

9007-83-4

Product Name Alternative

G-protein coupled receptor 161; G-protein coupled receptor RE2

Gene ID

23432

Accession Number

Q8N6U8

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human GP161 protein at amino acid sequence of 180-260

Clonality

Polyclonal

Tag

GP161

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

58kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GP161 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000