GKN2 Polyclonal Antibody

Rabbit Anti-GKN2 Polyclonal Antibody

Product Specifications

Background

The secretory protein encoded by GKN2 (Gastrokine 2) is produced in gastric surface mucous cells, where it can bind trefoil factor family peptide 1 or gastrokine-1. GKN2 may be a tumor suppressor gene, as its expression is markedly decreased in gastric cancer tissues. The encoded protein interacts with gastrokine-1 and regulates homeostasis of the gastric mucosa. GKN2 is a Protein Coding gene. Diseases associated with GKN2 include Gastric Cancer, Somatic and Internuclear Ophthalmoplegia.

CAS Number

9007-83-4

Product Name Alternative

Gastrokine-2; Blottin; Down-regulated in gastric cancer; Trefoil factor interactions (z) 1

Gene ID

200504

Accession Number

Q86XP6

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human GKN2 protein at amino acid sequence of 30-110

Clonality

Polyclonal

Tag

GKN2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

20kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GKN2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000