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GH Polyclonal Antibody

Rabbit Anti-GH Polyclonal Antibody

Product Specifications

Background

The Growth Hormone 1 encoded by GH1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. GH1, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

CAS Number

9007-83-4

Product Name Alternative

Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone

Gene ID

2688

Accession Number

P01241/P01242

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human GH protein at amino acid sequence of 180-217

Clonality

Polyclonal

Tag

GH

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of GH

Product Datasheet

https://www.abbkine.com/datasheet/ABP58637.pdf

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200

Other Product Names

Somatotropin; Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone Growth hormone variant; GH-V; Growth hormone 2; Placenta-specific growth hormone

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P01241

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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