Thiocholesterol

Thiocholesterol is a member of the class of cholesteric liquid crystals (CLCs) that can be used to synthesis cationic lipid. Thiocholesterol is a stronger stabilizer of silver nanoparticles (SNPs) . Thiocholesterol can be used for plasma membrane research and drug delivery[1][2].

Product Specifications

CAS Number

[1249-81-6]

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Liposome

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/thiocholesterol.html

Solubility

10 mM in DMSO

Smiles

CC(C)CCC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4C[C@@H](S)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C27H46S

Molecular Weight

402.72

Precautions

H302, H315, H319, H335

References & Citations

[1]Huang Z, et al. Thiocholesterol-based lipids for ordered assembly of bioresponsive gene carriers. Mol Ther. 2005 Mar;11 (3) :409-17.|[2]Ya. A. Gromova, et al. Adsorption Properties of Hybrid Metal–Mesogenic Silver–Cholesterol and Silver–Thiocholesterol Nanosystems. PHYSICAL CHEMISTRY OF NANOCLUSTERS AND NANOMATERIALS. 2019.