GELS Polyclonal Antibody
Rabbit Anti-GELS Polyclonal Antibody
Product Specifications
Background
Gelsolin encoded by GSN binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF) . Multiple transcript variants encoding several different isoforms have been found for GSN. GSN (Gelsolin) is a Protein Coding gene. Diseases associated with GSN include Amyloidosis, Finnish Type and Lattice Corneal Dystrophy Type Ii. Among its related pathways are Apoptosis and survival Caspase cascade and N-cadherin signaling events.
CAS Number
9007-83-4
Product Name Alternative
Gelsolin; AGEL; Actin-depolymerizing factor; ADF; Brevin
Gene ID
2934
Accession Number
P06396
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human GELS protein
Clonality
Polyclonal
Tag
GELS
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
86kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of GELS protein
Product Datasheet
https://www.abbkine.com/datasheet/ABP58629.pdf
Observed Molecular Weight
86
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Gelsolin; AGEL; Actin-depolymerizing factor; ADF; Brevin
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P06396
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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