Valanimycin
Product Specifications
UNSPSC Description
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A)-sensitive), and P388/ADR (doxorubicin-resistant), with IC50 of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice[1].
Target Antigen
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/valanimycin.html
Smiles
CC(C)C/[N+]([O-])=N/C(C(O)=O)=C
Molecular Weight
172.18
References & Citations
[1]Yamato M, et al., Isolation and properties of valanimycin, a new azoxy antibiotic. J Antibiot (Tokyo). 1986 Feb;39(2):184-91.|[2]Yamato M, et al., Valanimycin acts on DNA in bacterial cells. J Antibiot (Tokyo). 1987 Apr;40(4):558-60.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126170/Valanimycin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126170/
Clinical Information
No Development Reported
CAS Number
101961-60-8
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