Valanimycin
Valanimycin is an antibiotic, which inhibits Escherichia coli (BE1121) through interaction with DNA. Valanimycin exhibits cytotoxicity to mouse leukemia L1210, P388/S (doxorubicin (HY-15142A) -sensitive), and P388/ADR (doxorubicin-resistant), with IC50 of 0.79, 2.65, and 1.44 μg/mL, respectively. Valanimycin exhibits antitumor efficacy against ehrlich ascites tumors or L1210 in mice[1].
Product Specifications
CAS Number
[101961-60-8]
UNSPSC
12352211
Target
Antibiotic; Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/valanimycin.html
Smiles
CC(C)C/[N+]([O-])=N/C(C(O)=O)=C
Molecular Formula
C7H12N2O3
Molecular Weight
172.18
References & Citations
[1]Yamato M, et al., Isolation and properties of valanimycin, a new azoxy antibiotic. J Antibiot (Tokyo) . 1986 Feb;39 (2) :184-91.|[2]Yamato M, et al., Valanimycin acts on DNA in bacterial cells. J Antibiot (Tokyo) . 1987 Apr;40 (4) :558-60.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
476311 100 µL
BOC (Cell Adhesion Molecule-Related/Down-Regulated by Oncogenes, Cdon Homolog (Mouse) )
Sign In for Pricing
View Details MBS1092863-01 0.5 mg (E-Coli)
Recombinant Bacillus subtilis UPF0154 protein yneF (yneF), partial
Sign In for Pricing
View Details MBS1092863-02 0.05 mg (Baculovirus)
Recombinant Bacillus subtilis UPF0154 protein yneF (yneF), partial
Sign In for Pricing
View Details 
MBS1092863-03 0.5 mg (Yeast)
Recombinant Bacillus subtilis UPF0154 protein yneF (yneF), partial
Sign In for Pricing
View Details MBS1092863-04 0.05 mg (Mammalian-Cell)
Recombinant Bacillus subtilis UPF0154 protein yneF (yneF), partial
Sign In for Pricing
View Details