Diprovocim-X
Product Specifications
UNSPSC Description
Diprovocim-X (compound 35) is a potent TLR1/TLR2 (toll-like receptor 1/2) agonist, with EC50 values of 0.14 and 0.75 nM for hTLR1/TLR2 and mTLR1/TLR2, respectively. Diprovocim-X is a potent adjuvant in vivo in mice, and serves to stimulate the adaptive immune response[1].
Target Antigen
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/diprovocim-x.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(OCCCCCCCCCCCCNC([C@@H]1CN(C(C2=CC=C(C(N3C[C@@H](C(N[C@@H]4[C@@H](C5=CC=CC=C5)C4)=O)[C@H](C(N[C@@H]6[C@@H](C7=CC=CC=C7)C6)=O)C3)=O)C=C2)=O)C[C@H]1C(N[C@@H]8[C@@H](C9=CC=CC=C9)C8)=O)=O)CNC(OC(C)(C)C)=O
Molecular Weight
1134.41
References & Citations
[1]Yang MH, et al. Next-Generation Diprovocims with Potent Human and Murine TLR1/TLR2 Agonist Activity That Activate the Innate and Adaptive Immune Response. J Med Chem. 2022 Jun 29.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-150501/Diprovocim-X-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-150501/Diprovocim-X-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
3005274-77-8
Available Sizes
Curated Selection
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