EDN2 Polyclonal Antibody

Rabbit Anti-EDN2 Polyclonal Antibody

Product Specifications

Background

EDN2 encodes a member of the endothelin protein family of secretory vasoconstrictive peptides. Endothelin 2 is processed to a short mature form which functions as a ligand for the endothelin receptors that initiate intracellular signaling events. This gene product is involved in a wide range of biological processes, such as hypertension and ovulation. Altered expression of this gene is implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Endothelin-2; ET-2; Preproendothelin-2; PPET2

Gene ID

1907

Accession Number

P20800

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human EDN2 protein

Clonality

Polyclonal

Tag

EDN2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

19kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of EDN2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000