DSG3 Polyclonal Antibody
Rabbit Anti-DSG3 Polyclonal Antibody
Product Specifications
Background
DSG3 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG3 is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.
CAS Number
9007-83-4
Product Name Alternative
Desmoglein-3; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6
Gene ID
1830
Accession Number
P32926
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from part region of human DSG3 protein
Clonality
Polyclonal
Tag
DSG3
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
109kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DSG3 protein
Observed Molecular Weight
109
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Desmoglein-3; 130 kDa pemphigus vulgaris antigen; PVA; Cadherin family member 6
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P32926
Isotype
Rabbit IgG
Available Sizes
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