DSCAM Polyclonal Antibody

DSCAM is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs) and is involved in human central and peripheral nervous system development. DSCAM is a candidate for Down syndrome and congenital heart disease (DSCHD) . A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. DSCAM (DS Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with DSCAM include Down Syndrome-Related Congenital Heart Disease and Down Syndrome. Among its related pathways are Cell junction organization and Guidance Cues and Growth Cone Motility. An important paralog of this gene is DSCAML1.

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Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000