DRAM1 Polyclonal Antibody

Rabbit Anti-DRAM1 Polyclonal Antibody

Product Specifications

Background

DRAM1 is regulated as part of the p53 tumor suppressor pathway. DRAM1 encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of DRAM1 is associated with various tumors. This gene has a pseudogene on chromosome 4.

CAS Number

9007-83-4

Product Name Alternative

DNA damage-regulated autophagy modulator protein 1; Damage-regulated autophagy modulator

Gene ID

55332

Accession Number

Q8N682

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human DRAM1 protein at amino acid sequence of 151-200

Clonality

Polyclonal

Tag

DRAM1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

26kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of DRAM1 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000