DHB8 Polyclonal Antibody
Rabbit Anti-DHB8 Polyclonal Antibody
Product Specifications
Background
In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The Hydroxysteroid 17-Beta Dehydrogenase 8 encoded by HSD17B8 is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
CAS Number
9007-83-4
Product Name Alternative
Estradiol 17-beta-dehydrogenase 8; 17-beta-hydroxysteroid dehydrogenase 81 Publication; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit1 Publication; KAR alpha subunit1 Publication; 3-oxoacyl-[acyl-carrier-protein] reductase Protein Ke6; Ke-6; Really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8
Gene ID
7923
Accession Number
Q92506
Reactivity
Human, Rat, Mouse
Immunogen
Synthesized peptide derived from part region of human DHB8 protein
Clonality
Polyclonal
Tag
DHB8
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
28kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
The antibody detects endogenous levels of DHB8 protein
Observed Molecular Weight
28
Formulation
Liquid solution
Buffer pH
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000
Other Product Names
Estradiol 17-beta-dehydrogenase 8; 17-beta-hydroxysteroid dehydrogenase 81 Publication; 17-beta-HSD 8; 3-ketoacyl-[acyl-carrier-protein] reductase alpha subunit1 Publication; KAR alpha subunit1 Publication; 3-oxoacyl-[acyl-carrier-protein] reductase Protein Ke6; Ke-6; Really interesting new gene 2 protein; Short chain dehydrogenase/reductase family 30C member 1; Testosterone 17-beta-dehydrogenase 8
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q92506
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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