CRHBP Polyclonal Antibody

Rabbit Anti-CRHBP Polyclonal Antibody

Product Specifications

Background

Corticotropin-releasing hormone (CRHBP) is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

CAS Number

9007-83-4

Product Name Alternative

Corticotropin-releasing hormone-binding protein; CRH-BP; Corticotropin-releasing factor-binding protein; CRF-BP; CRF-binding protein

Gene ID

1393

Accession Number

P24387

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human CRHBP protein at amino acid sequence of 70-150

Clonality

Polyclonal

Tag

CRHBP

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

35kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CRHBP protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000