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CP3A5 Polyclonal Antibody

Rabbit Anti-CP3A5 Polyclonal Antibody

Product Specifications

Background

CYP3A5 (Cytochrome P450 Family 3 Subfamily A Member 5) is a Protein Coding gene. Diseases associated with CYP3A5 include Hypertension, Essential and Cyp3a5-Related Altered Drug Metabolism. Among its related pathways are Imipramine/Desipramine Pathway, Pharmacokinetics and Metabolism. CYP3A5 encodes a member of the cytochrome P450 superfamily of enzymes. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. CYP3A5 is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Cytochrome P450 3A5; CYPIIIA5; Cytochrome P450 HLp2; Cytochrome P450-PCN3

Gene ID

1577

Accession Number

P20815

Reactivity

Human

Immunogen

Synthesized peptide derived from part region of human CP3A5 protein at amino acid sequence of 200-280

Clonality

Polyclonal

Tag

CP3A5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

55kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CP3A5 protein

Observed Molecular Weight

55

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Cytochrome P450 3A5; CYPIIIA5; Cytochrome P450 HLp2; Cytochrome P450-PCN3

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P20815

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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