Collagen XI α1 Polyclonal Antibody

Rabbit Anti-Collagen XI α1 Polyclonal Antibody

Product Specifications

Background

COL11A1 encodes one of the two alpha chains of type XI collagen, a minor fibrillar collagen. Type XI collagen is a heterotrimer but the third alpha chain is a post-translationally modified alpha 1 type II chain. Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome. A single-nucleotide polymorphism in COL11A1 is also associated with susceptibility to lumbar disc herniation. Multiple transcript variants have been identified for COL11A1.

CAS Number

9007-83-4

Product Name Alternative

Collagen alpha-1; XI chain

Gene ID

1301

Accession Number

P12107

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human Collagen XI α1 protein

Clonality

Polyclonal

Tag

Collagen XI α1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

180kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

This antibody detects endogenous levels of Collagen XI α1.

Observed Molecular Weight

180

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000