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CLCN1 Polyclonal Antibody

Rabbit Anti-CLCN1 Polyclonal Antibody

Product Specifications

Background

CLCN1 (Chloride Voltage-Gated Channel 1) is a Protein Coding gene. Diseases associated with CLCN1 include Myotonia Congenita, Recessive and Myotonia Congenita, Dominant The protein encoded by CLCN1 regulates the electric excitability of the skeletal muscle membrane. Mutations in CLCN1 cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen) . Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Chloride channel protein 1; ClC-1; Chloride channel protein, skeletal muscle

Gene ID

1180

Accession Number

P35523

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human CLCN1 protein

Clonality

Polyclonal

Tag

CLCN1

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

108kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CLCN1 protein

Product Datasheet

https://www.abbkine.com/datasheet/ABP58180.pdf

Observed Molecular Weight

108

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Chloride channel protein 1; ClC-1; Chloride channel protein, skeletal muscle

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P35523

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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