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CLAP2 Polyclonal Antibody

Rabbit Anti-CLAP2 Polyclonal Antibody

Product Specifications

Background

CLASP2 (Cytoplasmic Linker Associated Protein 2) is a Protein Coding gene. Diseases associated with CLASP2 include Clostridium Difficile Colitis. Among its related pathways are DNA Damage and Cell Cycle, Mitotic. Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN) . Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex.

CAS Number

9007-83-4

Product Name Alternative

CLIP-associating protein 2; Cytoplasmic linker-associated protein 2; Protein Orbit homolog 2; hOrbit2

Gene ID

23122

Accession Number

O75122

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human CLAP2 protein

Clonality

Polyclonal

Tag

CLAP2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

142kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CLAP2 protein

Observed Molecular Weight

142

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

CLIP-associating protein 2; Cytoplasmic linker-associated protein 2; Protein Orbit homolog 2; hOrbit2

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/O75122

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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