Nitroprusside (disodium dihydrate)

Nitroprusside disodium dehydrate (Sodium nitroprusside dihydrate) is a vasodilator that available for the research of acute hypertension, heart failure. Nitroprusside disodium dehydrate induces autophagy in glutathione-depleted osteoblasts. Nitroprusside disodium dehydrate acts as a nitric oxide (NO) donor in a rat intestinal ischemia reperfusion model[1][2][3][4].

Product Specifications

CAS Number

[13755-38-9]

Product Name Alternative

Sodium nitroprusside dihydrate; Sodium Nitroferricyanide (III) Dihydrate

UNSPSC

12352300

Hazard Statement

H301

Target

Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/Nitroprusside-disodium-dihydrate.html

Purity

99.87

Solubility

DMSO : 50 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

[Na2[Fe(CN)5NO].2H2O]

Molecular Formula

C5FeN6O.2H2O.2Na

Molecular Weight

297.95

Precautions

H301

References & Citations

[1]Namazi, H., Sodium nitroprusside as a nitric oxide donor in a rat intestinal ischemia reperfusion model: a novel molecular mechanism. Clinics (Sao Paulo), 2008. 63 (3) : p. 405.|[2]J N Cohn, et al. Nitroprusside. Ann Intern Med. 1979 Nov;91 (5) :752-7.|[3]Min Jeong Son, et al. Sodium nitroprusside induces autophagic cell death in glutathione-depleted osteoblasts. J Biochem Mol Toxicol. Sep-Oct 2010;24 (5) :313-22.|[4]Liuqin Yang, et al. Sodium nitroprusside (SNP) sensitizes human gastric cancer cells to TRAIL-induced apoptosis. Int Immunopharmacol. 2013 Oct;17 (2) :383-9.