CDKL5 Polyclonal Antibody

Rabbit Anti-CDKL5 Polyclonal Antibody

Product Specifications

Background

CDKL5 is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in CDKL5 have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT) . Alternate transcriptional splice variants have been characterized.

CAS Number

9007-83-4

Product Name Alternative

Cyclin-dependent kinase-like 5; Serine/threonine-protein kinase 9

Gene ID

6792

Accession Number

O76039

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human CDKL5 protein at amino acid sequence of 30-110

Clonality

Polyclonal

Tag

CDKL5

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

113kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CDKL5 protein

Observed Molecular Weight

113

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000