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CD70 Polyclonal Antibody

Rabbit Anti-CD70 Polyclonal Antibody

Product Specifications

Background

The protein encoded by CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling. is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. CD70 (CD70 Molecule) is a Protein Coding gene. Diseases associated with CD70 include Acute Myocarditis and Lymphoproliferative Syndrome 2. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Akt Signaling.

CAS Number

9007-83-4

Product Name Alternative

CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70

Gene ID

970

Accession Number

P32970

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human CD70 protein at amino acid sequence of 150-193

Clonality

Polyclonal

Tag

CD70

Applications

IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CD70

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200

Other Product Names

CD70 antigen; CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P32970

Isotype

Rabbit IgG

Available Sizes

Frequently Asked Questions

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