CCNL2 Polyclonal Antibody

Rabbit Anti-CCNL2 Polyclonal Antibody

Product Specifications

Background

The protein encoded by CCNL2 (Cyclin L2) belongs to the cyclin family. Through its interaction with several proteins, such as RNA polymerase II, splicing factors, and cyclin-dependent kinases, this protein functions as a regulator of the pre-mRNA splicing process, as well as in inducing apoptosis by modulating the expression of apoptotic and antiapoptotic proteins. Alternatively spliced transcript variants encoding different isoforms have been described for CCNL2. Diseases associated with CCNL2 include Star Syndrome.

CAS Number

9007-83-4

Product Name Alternative

Cyclin-L2; Paneth cell-enhanced expression protein

Gene ID

81669

Accession Number

Q96S94

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human CCNL2 protein at amino acid sequence of 400-480

Clonality

Polyclonal

Tag

CCNL2

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

57kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CCNL2 protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000