CALCR Polyclonal Antibody

Rabbit Anti-CALCR Polyclonal Antibody

Product Specifications

Background

CALCR encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in CALCR have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Calcitonin receptor; CT-R

Gene ID

799

Accession Number

P30988

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human CALCR protein at amino acid sequence of 410-490

Clonality

Polyclonal

Tag

CALCR

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

53kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of CALCR protein

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000