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Calcitonin Polyclonal Antibody

Rabbit Anti-Calcitonin Polyclonal Antibody

Product Specifications

Background

CALCA encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator and as an antimicrobial peptide while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for CALCA. CALCA (Calcitonin Related Polypeptide Alpha) is a Protein Coding gene. Diseases associated with CALCA include Reflex Sympathetic Dystrophy and Complex Regional Pain Syndrome. Among its related pathways are G alpha (s) signalling events and Signaling by GPCR.

CAS Number

9007-83-4

Product Name Alternative

Calcitonin

Gene ID

796

Accession Number

P01258

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human Calcitonin protein at amino acid sequence of 80-141

Clonality

Polyclonal

Tag

Calcitonin

Applications

WB, IHC, IF, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

16kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of Calcitonin

Observed Molecular Weight

16

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 100-300; WB 1:500-2000; ELISA 1:10000-20000; IF 1:50-200

Other Product Names

Calcitonin

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P01258

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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