APTX Polyclonal Antibody

Rabbit Anti-APTX Polyclonal Antibody

Product Specifications

Background

APTX encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in APTX have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for APTX.

CAS Number

9007-83-4

Product Name Alternative

Aprataxin; Forkhead-associated domain histidine triad-like protein; FHA-HIT

Gene ID

54840

Accession Number

Q7Z2E3

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human APTX protein at amino acid sequence of 11-60

Clonality

Polyclonal

Tag

APTX

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

39kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of APTX protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000