ANO10 Polyclonal Antibody

Rabbit Anti-ANO10 Polyclonal Antibody

Product Specifications

Background

The transmembrane protein encoded by ANO10 belongs to the anoctamin family of calcium-activated chloride channels, also known as the transmembrane 16 family. The encoded protein contains eight transmembrane domains with cytosolic N- and C-termini. Defects in ANO10 may cause autosomal recessive spinocerebellar ataxia-10. Alternative splicing results in multiple transcript variants.

CAS Number

9007-83-4

Product Name Alternative

Anoctamin-10; Transmembrane protein 16K

Gene ID

55129

Accession Number

Q9NW15

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human ANO10 protein at amino acid sequence of 431-480

Clonality

Polyclonal

Tag

ANO10

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

72kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of ANO10 protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000