AGO3 Polyclonal Antibody

Rabbit Anti-AGO3 Polyclonal Antibody

Product Specifications

Background

AGO03 encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. AGO03 is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene. AGO3 (Argonaute 3, RISC Catalytic Component) is a Protein Coding gene. Among its related pathways are RET signaling and Translational Control.

CAS Number

9007-83-4

Product Name Alternative

Protein argonaute-3; Argonaute3; Argonaute3; Argonaute RISC catalytic component 3; Eukaryotic translation initiation factor 2C 3; eIF-2C 3

Gene ID

192669

Accession Number

Q9H9G7

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from part region of human AGO3 protein

Clonality

Polyclonal

Tag

AGO3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

94kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of AGO3 protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000