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ADA Polyclonal Antibody

Rabbit Anti-ADA Polyclonal Antibody

Product Specifications

Background

ADA (Adenosine Deaminase) is a Protein Coding gene. Diseases associated with ADA include Severe Combined Immunodeficiency Due To Ada Deficiency and Adenosine Deaminase Deficiency. Among its related pathways are Metabolism and One carbon pool by folate. ADA encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for ADA and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

CAS Number

9007-83-4

Product Name Alternative

Adenosine deaminase; Adenosine aminohydrolase

Gene ID

100

Accession Number

P00813

Reactivity

Human, Rat, Mouse

Immunogen

Synthesized peptide derived from part region of human ADA protein at amino acid sequence of 80-160

Clonality

Polyclonal

Tag

ADA

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

39kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of ADA protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Adenosine deaminase; Adenosine aminohydrolase

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/P00813

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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