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ACHB3 Polyclonal Antibody

Rabbit Anti-ACHB3 Polyclonal Antibody

Product Specifications

Background

CHRNB3 (Cholinergic Receptor Nicotinic Beta 3 Subunit) is a Protein Coding gene. Diseases associated with CHRNB3 include Duane Retraction Syndrome and Autosomal Dominant Nocturnal Frontal Lobe Epilepsy. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Acetylcholine Binding And Downstream Events. The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel.

CAS Number

9007-83-4

Product Name Alternative

Neuronal acetylcholine receptor subunit beta-3

Gene ID

1142

Accession Number

Q05901

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from part region of human ACHB3 protein at amino acid sequence of 160-240

Clonality

Polyclonal

Tag

ACHB3

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

50kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous levels of ACHB3 protein

Formulation

Liquid solution

Buffer pH

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:5000-20000

Other Product Names

Neuronal acetylcholine receptor subunit beta-3

Tested Applications

WB, IHC, IF, IP, ELISA

Host or Source

Rabbit

Accession Number URL

http://www.uniprot.org/uniprot/Q05901

Isotype

Rabbit IgG

Available Sizes

Curated Selection

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