HLA Class I Polyclonal Antibody

Rabbit Anti-HLA Class I Polyclonal Antibody

Product Specifications

Background

Human major histocompatibility complex (MHC) antigens, also referred to as human leukocyte antigens (HLA), are encoded by genes located on the short arm of chromosome 6. There are two classes of HLA antigens: class I (HLA-A, B and C) and class II (HLA-D) . This class I molecules are polymorphic membrane glycoproteins composed of a heavy (alpha) chain (44 kDa) which is encoded by a HLA class I gene (HLA-A, B or C), and β2-microglobulin light (beta) chain (12 kDa) . They are involved in the presentation of foreign antigens to the immune system. (PMID: 667938; 3375250)

CAS Number

9007-83-4

Product Name Alternative

HLA-A; HLAA

Accession Number

P01891/P01892/P04439/P05534/P10314/P10316/P13746/P16189/P18462/P30443/P30450/P30453/P30455/P30456/P30457/P30512/Q09160

Reactivity

Human

Immunogen

Synthetic peptide from human protein at AA range: 220-270

Clonality

Polyclonal

Tag

Major histocompatibility complex, class I

Applications

WB, ELISA

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Molecular Weight

40kD

Precautions

The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Shipping Conditions

Gel pack with blue ice.

Storage Conditions

Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Notes

The antibody detects endogenous HLA Class I protein.

Observed Molecular Weight

Formulation

Liquid solution

Buffer pH

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Applications Notes

Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000