SK33
SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity[1].
Product Specifications
CAS Number
[1928724-23-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Androgen Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sk33.html
Purity
99.98
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)COC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2
Molecular Formula
C20H13F9N2O3
Molecular Weight
500.31
Precautions
H302, H315, H319
References & Citations
[1]Dart DA, et al. Novel Trifluoromethylated Enobosarm Analogues with Potent Antiandrogenic Activity In Vitro and Tissue Selectivity In Vivo.Mol Cancer Ther. 2018 Sep;17 (9) :1846-1858.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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