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SK33

SK33, a trifluoromethylated enobosarm analog, is a potent, and tissue selective anti-androgen. SK33reduces androgen receptor (AR) transcriptional activity[1].

Product Specifications

CAS Number

[1928724-23-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sk33.html

Purity

99.98

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(C#N)C(C(F)(F)F)=C1)C(C)(O)COC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2

Molecular Formula

C20H13F9N2O3

Molecular Weight

500.31

Precautions

H302, H315, H319

References & Citations

[1]Dart DA, et al. Novel Trifluoromethylated Enobosarm Analogues with Potent Antiandrogenic Activity In Vitro and Tissue Selectivity In Vivo.Mol Cancer Ther. 2018 Sep;17 (9) :1846-1858.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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