Beclin-1 Polyclonal Antibody
Rabbit Anti-Beclin-1 Polyclonal Antibody
Product Specifications
Background
BECN1 (beclin 1) encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.
Product Name Alternative
Beclin 1, autophagy related
Gene ID
8678
Accession Number
Q14457
Reactivity
Human, Mouse, Chicken
Immunogen
Synthesized peptide derived from Beclin-1 at AA range: 110-190
Clonality
Polyclonal
Tag
Beclin-1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
55kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Beclin-1 Polyclonal Antibody detects endogenous levels of Beclin-1.
Product Datasheet
https://www.abbkine.com/datasheet/ABP57488.pdf
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000; ELISA 1:10000-20000
Other Product Names
Beclin 1, autophagy related
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q14457
CAS Number
9007-83-4
Isotype
Rabbit IgG
Available Sizes
Curated Selection
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